Diagnostics Simplified

Blood testing with no hassles, no delays and no instrument. Xip produces disposable blood analyzers that wirelessly upload lab-quality clinical measurements in minutes. For example, these devices can be deployed in Emergency Departments (EDs) to simplify the process of diagnosing heart attacks by providing on-demand, high-sensitivity biomarker measurements.


NASA Earth Space Life Science Innovation Prize

XPrize – Nokia Sensing XChallenge Distinguished Award

Three Small Business Innovation Research Grants

Haas Business Plan Competition – People’s Choice Award

Heart attack or heart burn?

Of the 10 million patients presenting annually to EDs in the US with the symptoms, less than 20% are ultimately diagnosed with a heart attack. Accurate and timely troponin measurements are crucial for identifying heart muscle necrosis and effectively triaging patients. However, central labs are hard-pressed to return results in under one hour, while point-of-care systems require unwieldy instruments and often cannot detect low yet meaningful levels of troponin. Xip Troponin will allow ED professionals to more quickly and easily triage patients suspected of a heart attack, saving thousands of lives and billions of dollars.

Heart Blockage


Lab-quality results
in minutes



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Central lab on a microchip

At the core of the Xip platform lies a Digital Molecule Counter – a fully integrated CMOS microchip that combines on-chip magnetic separation to eliminate non-specific binding with an array of 40,000 single molecule sensors. Multiple proteins, nucleic acids and small molecules can be measured simultaneously from one drop of blood, on the go. The single-use disposables are produced inexpensively using existing high-volume semiconductor manufacturing capacity.

To benchmark performance, troponin was measured using the Xip device on patients presenting to the University of Maryland Medical Center with the symptoms of a heart attack. Results showed a tight correlation to the gold standard laboratory system. The prototype of the Xip platform was completed in late 2015 and market roll-out is expected in 2018.


Point of need testing

Clinical results from a 30μL drop of blood appear on the digital display and are securely uploaded to an EMR or a nearby phone. After use, the device is discarded but the data retained and analyzed. Room-temperature stable dry chemistry and the absence of sample preparation make the Xip device as easy to use as a glucometer, but with the menu of a clinical analyzer. This flexibility will allow patients, physicians and broader medical systems to more efficiently access and handle vital diagnostic information.




Infectious Diseases


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